SCHEMBL17066419

SCHEMBL17066419

CCNc1cc(OCc2ccccc2)ccc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.50
MAOA P21397 2/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALOX5 P09917 1/20 0.49
BCHE P06276 2/20 0.44
AS3MT Q9HBK9 1/20 0.44
LNPEP Q9UIQ6 2/20 0.44
CYP3A4 P08684 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
CYP2C19 P33261 1/20 0.44
PTGS2 P35354 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9893532 0.99 MAOB (0.49) MAOBMAOAGAAMAPTRAB9A
SCHEMBL19586631 0.85 MAOB (0.53) MAOBMAOAGAAMAPTRAB9A
Hydrochloric Acid SCHEMBL9893278 0.84 MAOB (0.51) MAOBMAOAGAAMAPTRAB9A
Hydrochloric Acid SCHEMBL9893513 0.83 MAOB (0.46) MAOBMAOAGAAMAPTRAB9A
SCHEMBL20283156 0.82 LNPEP (0.45) MAOBMAOAGAAMAPTRAB9A
SCHEMBL3994495 0.81 MAOB (0.53) MAOBGAAMAPTRAB9ASMN1; SMN2
SCHEMBL22962452 0.81 ALOX5 (0.47) MAOBMAOAGAAMAPTSMN1; SMN2
SCHEMBL2345729 0.81 MAOB (0.49) MAOBMAOAGAAMAPTRAB9A
SCHEMBL23356660 0.81 MAOB (0.46) MAOBMAOAGAAMAPTRAB9A
SCHEMBL8698357 0.80 LNPEP (0.45) MAOBMAOAGAAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9126985-B2 Tetra- and pentasubstituted benzimidazolium compounds BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-08 US disclosed