SCHEMBL17066437

SCHEMBL17066437

Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3cccc4c3OCC4)C(F)(F)F)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 1.00
PGR P06401 3/20 1.00
NR3C2 P08235 3/20 1.00
AR P10275 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30335364 1.00 NR3C1 (1.00) NR3C1PGRNR3C2AR
SCHEMBL6077179 0.91 NR3C1 (0.83) NR3C1PGRNR3C2AR
SCHEMBL6076827 0.87 NR3C1 (0.78) NR3C1PGRNR3C2AR
SCHEMBL14602512 0.87 NR3C1 (0.78) NR3C1PGRNR3C2AR
SCHEMBL24252000 0.86 NR3C1 (0.76) NR3C1PGRNR3C2AR
SCHEMBL5644055 0.85 NR3C1 (0.74) NR3C1PGRNR3C2AR
SCHEMBL5641166 0.85 NR3C1 (0.74) NR3C1PGRNR3C2AR
SCHEMBL5642432 0.84 NR3C1 (0.73) NR3C1PGRNR3C2AR
SCHEMBL4621610 0.84 NR3C1 (0.73) NR3C1PGRNR3C2AR
SCHEMBL4622412 0.84 NR3C1 (0.73) NR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725558-A2 IMMUNOABLATIVE THERAPIES AVM Biotechnology, LLC (US) 2026-04-15 EP disclosed
EP-3860612-B1 IMMUNOABLATIVE THERAPIES AVM BIOTECHNOLOGY LLC (US) 2026-03-04 EP disclosed
EP-3768324-B1 METHODS FOR MODULATING INNATE LYMPHOID CELL ACTIVITY, ANTIBODY DRUG CONJUGATES AND USES IN THERAPY INST NAT SANTE RECH MED (FR) 2025-11-26 EP disclosed
US-12048705-B2 Immunoablative therapies AVM BIOTECHNOLOGY, LLC (US) 2024-07-30 US disclosed
EP-3632446-B3 IMMUNOABLATIVE THERAPIES AVM BIOTECHNOLOGY LLC (US) 2024-01-24 EP disclosed
EP-3490605-B1 REPLACEMENT OF CYTOTOXIC PRECONDITIONING BEFORE CELLULAR IMMUNOTHERAPY AVM BIOTECHNOLOGY LLC (US) 2023-06-07 EP disclosed
US-11446314-B2 Immunoablative therapies AVM BIOTECHNOLOGY, LLC (US) 2022-09-20 US disclosed
US-20220160729-A1 Replacement of Cytotoxic Preconditioning Before Cellular Immunotherapy AVM BIOTECHNOLOGY, LLC (US) 2022-05-26 US disclosed
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) ST. ANNA KINDERKREBSFORSCHUNG (AT) 2022-02-10 US disclosed
US-11219628-B2 Replacement of cytotoxic preconditioning before cellular immunotherapy AVM BIOTECHNOLOGY, LLC (US) 2022-01-11 US disclosed
US-20200108078-A1 IMMUNOABLATIVE THERAPIES AVM BIOTECHNOLOGY, LLC 2020-04-09 US disclosed
EP-3632460-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) St. Anna Kinderkrebsforschung (AT) 2020-04-08 EP disclosed
EP-3632461-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) St. Anna Kinderkrebsforschung (AT) 2020-04-08 EP disclosed
EP-3632446-A1 IMMUNOABLATIVE THERAPIES AVM Biotechnology, LLC (US) 2020-04-08 EP disclosed
EP-3490605-A1 REPLACEMENT OF CYTOTOXIC PRECONDITIONING BEFORE CELLULAR IMMUNOTHERAPY AVM Biotechnology, LLC (US) 2019-06-05 EP disclosed
EP-3488851-A1 IMMUNOABLATIVE THERAPIES AVM Biotechnology, LLC (US) 2019-05-29 EP disclosed
US-20180296572-A1 REPLACEMENT OF CYTOTOXIC PRECONDITIONING BEFORE CELLULAR IMMUNOTHERAPY AVM BIOTECHNOLOGY, LLC (US) 2018-10-18 US disclosed
WO-2018183927-A1 REPLACEMENT OF CYTOTOXIC PRECONDITIONING BEFORE CELLULAR IMMUNOTHERAPY AVM BIOTECHNOLOGY, LLC (US) 2018-10-04 WO disclosed
US-20150250873-A1 COMBINATION THERAPY OF ANTI-MIF ANTIBODIES AND GLUCOCORTICOIDS Baxalta GmbH (CH) 2015-09-10 US disclosed
US-9126997-B1 Synergistic effect of glucocorticoid receptor agonists in combination with proteosome inhibitors for treating leukemia and myeloma NORTHWESTERN UNIVERSITY (US) 2015-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250873-A1 COMBINATION THERAPY OF ANTI-MIF ANTIBODIES AND GLUCOCORTICOIDS MIF, NR3C2, NR3C1 NR3C1 3/4885PGR 117/4885NR3C2 2/4885
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CARS1, CD74, HAVCR2 NR3C1 2873/4885PGR 4023/4885NR3C2 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.