Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18467579 | 0.86 | MAPT (0.43) | CYP2C9SMN1; SMN2CA1MAOBPTGS2 | |
| SCHEMBL14817765 | 0.85 | APP (0.40) | LMNASMN1; SMN2CA1CA2MAOB | |
| SCHEMBL19872825 | 0.85 | GLA (0.42) | F3CYP2D6CYP2C9LMNASMN1; SMN2 | |
| SCHEMBL21770851 | 0.83 | — | — | |
| SCHEMBL14986873 | 0.82 | HSD17B3 (0.51) | CYP2D6SMN1; SMN2MAOBAPPMAOA | |
| SCHEMBL19622458 | 0.82 | CA12 (0.42) | TYRF3CYP2D6CYP2C9HSD11B1 | |
| SCHEMBL23745136 | 0.81 | JUN (0.46) | CYP2D6CYP2C9LMNASMN1; SMN2PKM | |
| SCHEMBL15359141 | 0.79 | ALDH1A1 (0.35) | LMNAGAASMN1; SMN2RAB9APOLB | |
| SCHEMBL15359132 | 0.79 | APP (0.32) | SMN1; SMN2APPRAB9A | |
| SCHEMBL14986896 | 0.79 | ALDH1A1 (0.46) | CYP2D6LMNAGAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125973-B2 | Antimicrobial housing and cover for a medical device | BAXTER INTERNATIONAL INC. (US) | 2015-09-08 | — | — | US | disclosed |