Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 7/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | STARD10 | Q9Y365 | 3/20 | 0.54 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235185 | 0.89 | PCTP (1.00) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL17066524 | 0.86 | PCTP (0.79) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL17066528 | 0.82 | PCTP (0.78) | PCTPALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL17066575 | 0.82 | PCTP (0.77) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL17066490 | 0.79 | PCTP (0.79) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL12903628 | 0.78 | PCTP (0.77) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL17066590 | 0.75 | PCTP (0.79) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1235095 | 0.75 | PCTP (1.00) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL17066525 | 0.74 | PCTP (0.78) | PCTPALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL12903625 | 0.73 | NPSR1 (0.71) | PCTPALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556129-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150336902-A1 | Phosphatidylcholine Transfer Protein Inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2015-11-26 | — | — | US | disclosed |
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336902-A1 | Phosphatidylcholine Transfer Protein Inhibitors | PCTP, LCAT, CETP | PCTP 1/4885ALDH1A1 4289/4885LMNA 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.