Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 7/20 | 0.79 |
| ▸ | STARD10 | Q9Y365 | 2/20 | 0.56 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HTR1E | P28566 | 3/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235095 | 0.88 | PCTP (1.00) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL17066522 | 0.86 | PCTP (0.80) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL17066575 | 0.84 | PCTP (0.77) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL12903628 | 0.81 | PCTP (0.77) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL17066590 | 0.77 | PCTP (0.79) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL17066525 | 0.77 | PCTP (0.78) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL16358447 | 0.75 | PCTP (0.51) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL17066491 | 0.75 | SMN1; SMN2 (0.58) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL16358245 | 0.75 | ALDH1A1 (0.80) | PCTPSTARD10STARD7ALDH1A1LMNA | |
| SCHEMBL1235185 | 0.75 | PCTP (1.00) | PCTPSTARD10STARD7ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556129-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150336902-A1 | Phosphatidylcholine Transfer Protein Inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2015-11-26 | — | — | US | disclosed |
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336902-A1 | Phosphatidylcholine Transfer Protein Inhibitors | PCTP, LCAT, CETP | PCTP 1/4885STARD10 1028/4885STARD7 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.