Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.66 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PPIA | P62937 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066582 | 0.90 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL13470114 | 0.90 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL17066610 | 0.88 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL17066557 | 0.87 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL13453809 | 0.87 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL13470086 | 0.87 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL17066578 | 0.86 | GPR55 (0.76) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL17066560 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL13469997 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL13453825 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1ALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |