SCHEMBL17067285

SCHEMBL17067285

CN(CC(F)(F)F)C(=O)C(=O)Nc1cccc(C(=O)Nc2c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
PTGES O14684 10/20 0.36
RXFP1 Q9HBX9 6/20 0.36
RBP4 P02753 1/20 0.33
F2R P25116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17067317 0.94 RXFP1 (0.36) SMN1; SMN2PTGESRXFP1F2R
SCHEMBL17067298 0.91 PTGES (0.39) PTGESRXFP1
SCHEMBL17067341 0.90 RXFP1 (0.34) PTGESRXFP1RBP4
SCHEMBL17067315 0.90 RXFP1 (0.36) SMN1; SMN2PTGESRXFP1
SCHEMBL17067299 0.88 RXFP1 (0.34) SMN1; SMN2PTGESRXFP1F2R
SCHEMBL17067319 0.87 RXFP1 (0.33) SMN1; SMN2RXFP1F2R
SCHEMBL17067290 0.86 SMN1; SMN2 (0.34) SMN1; SMN2PTGESRXFP1F2R
SCHEMBL17067323 0.86 RXFP1 (0.32) PTGESRXFP1F2R
SCHEMBL17067284 0.86 DHODH (0.35) SMN1; SMN2RXFP1F2R
SCHEMBL1766615 0.83 SMN1; SMN2 (0.46) SMN1; SMN2PTGESRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US disclosed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US disclosed
EP-2915530-A1 COMPOSITION FOR ANIMAL PARASITE EXTERMINATION AND METHOD FOR ANIMAL PARASITE EXTERMINATION Mitsui Chemicals Agro, Inc. (JP) 2015-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE HDHD5, H1-3, TUBA3C SMN1; SMN2 4723/4885PTGES 4131/4885RXFP1 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.