SCHEMBL17067289

SCHEMBL17067289

CN(CC(F)(F)F)C(=O)C(=O)Nc1cccc(C(=O)Nc2c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Br)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 3/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
RAB9A P51151 2/20 0.38
HTT P42858 1/20 0.38
KCNK9 Q9NPC2 3/20 0.38
RXFP1 Q9HBX9 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
F2R P25116 1/20 0.36
RHOC P08134 1/20 0.36
RHOA P61586 1/20 0.36
PTGS1 P23219 1/20 0.36
KCNJ11 Q14654 1/20 0.36
PTGES O14684 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17067314 0.94 MAPT (0.40) KCNK3MAPTLMNAKMT2AMEN1
SCHEMBL17067288 0.90 MEN1 (0.42) KCNK3MAPTLMNAKMT2AMEN1
SCHEMBL17067316 0.82 MEN1 (0.37) KCNK3MAPTLMNAKMT2AMEN1
SCHEMBL17067317 0.81 RXFP1 (0.36) RAB9ARXFP1SMN1; SMN2F2RPTGES
SCHEMBL1767376 0.77 KCNK3 (0.54) KCNK3MAPTLMNAKMT2AMEN1
SCHEMBL17067285 0.76 SMN1; SMN2 (0.38) RXFP1SMN1; SMN2F2RPTGES
SCHEMBL1766416 0.76 MAPT (0.57) KCNK3MAPTLMNAKMT2AMEN1
SCHEMBL17067299 0.74 RXFP1 (0.34) RAB9ARXFP1SMN1; SMN2F2RPTGES
SCHEMBL1766829 0.74 KMT2A (0.52) KCNK3MAPTLMNAKMT2AMEN1
SCHEMBL17067319 0.73 RXFP1 (0.33) MAPTRXFP1SMN1; SMN2F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US disclosed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US disclosed
EP-2915530-A1 COMPOSITION FOR ANIMAL PARASITE EXTERMINATION AND METHOD FOR ANIMAL PARASITE EXTERMINATION Mitsui Chemicals Agro, Inc. (JP) 2015-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE HDHD5, H1-3, TUBA3C KCNK3 730/4885MAPT 4800/4885LMNA 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.