SCHEMBL17067294

SCHEMBL17067294

Cc1cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc(OC(F)F)c1NC(=O)c1cccc(N(C)C(=O)C(=O)N(C)CC(F)(F)F)c1F

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 7/20 0.33
SCN8A Q9UQD0 2/20 0.32
SCN10A Q9Y5Y9 2/20 0.32
RXFP1 Q9HBX9 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
UGCG Q16739 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17067302 0.93 DHODH (0.37) DHODHSCN8ASCN10ARXFP1NPC1
SCHEMBL17067330 0.88 DHODH (0.34) DHODHSCN8ASCN10ARXFP1UGCG
SCHEMBL17067300 0.85 DHODH (0.36) DHODHRXFP1
SCHEMBL17190127 0.81 DHODH (0.38) DHODHSCN8ASCN10AALDH1A1LMNA
SCHEMBL17067293 0.81 DHODH (0.38) DHODHSCN8ASCN10ARXFP1ALDH1A1
SCHEMBL24613026 0.80 DHODH (0.34) DHODHSCN8ASCN10ANPC1RAB9A
SCHEMBL17067329 0.79
SCHEMBL17067303 0.78 RXFP1 (0.33) RXFP1
SCHEMBL20846705 0.77 HTT (0.36) DHODHSCN8ASCN10ARXFP1ALDH1A1
SCHEMBL20846715 0.77 HTT (0.34) DHODHSCN8ASCN10ARXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US disclosed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US disclosed
EP-2915530-A1 COMPOSITION FOR ANIMAL PARASITE EXTERMINATION AND METHOD FOR ANIMAL PARASITE EXTERMINATION Mitsui Chemicals Agro, Inc. (JP) 2015-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE HDHD5, H1-3, TUBA3C DHODH 2281/4885SCN8A 1801/4885SCN10A 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.