Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067708 | 0.78 | USP7 (0.39) | — | |
| SCHEMBL14934100 | 0.76 | PIK3CD (0.50) | CHRNB2CHRNA4 | |
| SCHEMBL14934099 | 0.73 | IDO1 (0.44) | CHRNB2CHRNA4 | |
| SCHEMBL25699202 | 0.73 | RAF1 (0.39) | CHRNB2CHRNA4VRK1 | |
| SCHEMBL23277179 | 0.71 | CYP2A6 (0.46) | — | |
| SCHEMBL30919693 | 0.71 | CYP2A6 (0.46) | — | |
| SCHEMBL17067677 | 0.70 | KDM4E (0.42) | — | |
| SCHEMBL14934102 | 0.70 | CYP2A6 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL17067678 | 0.69 | JAK2 (0.39) | CHRNB2CHRNA4VRK1 | |
| SCHEMBL2554717 | 0.69 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |