Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 9/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067679 | 0.78 | CHRNB2 (0.36) | — | |
| SCHEMBL17067696 | 0.73 | IDO1 (0.44) | MAP4K4CYP1A2KCNH2MINK1TNIK | |
| SCHEMBL473823 | 0.71 | GPBAR1 (0.33) | USP7MAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL14934136 | 0.71 | CYP2A6 (0.46) | USP7MAP4K4DHFRALOX5APFEN1 | |
| SCHEMBL14934141 | 0.71 | GAA (0.46) | USP7MAP4K4DHFRALOX5APFEN1 | |
| SCHEMBL23277179 | 0.71 | CYP2A6 (0.46) | MAP4K4HPGD | |
| SCHEMBL30919693 | 0.71 | CYP2A6 (0.46) | MAP4K4HPGD | |
| SCHEMBL14934133 | 0.70 | USP7 (0.46) | USP7MAP4K4DHFRALOX5APFEN1 | |
| SCHEMBL3647945 | 0.69 | MAP4K4 (0.62) | USP7MAP4K4FYN | |
| SCHEMBL14934137 | 0.69 | JAK2 (0.48) | USP7MAP4K4DHFRPIK3CDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |