Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198349 | 0.92 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL20696479 | 0.92 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL19291899 | 0.91 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15495149 | 0.90 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL19291834 | 0.87 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10067025 | 0.87 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL24490907 | 0.86 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18400492 | 0.85 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15682924 | 0.85 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL24490797 | 0.84 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175667-A1 | Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices | THE JOHNS HOPKINS UNIVERSITY | 2022-06-09 | — | — | US | disclosed |
| US-20210069375-A1 | Extracellular Matrices, Uses thereof, and Method for Making Extracellular Matrices | THE JOHNS HOPKINS UNIVERSITY | 2021-03-11 | — | — | US | disclosed |
| US-10662532-B2 | Methods of manufacturing embossing elements | AGFA-GEVAERT N.V. (BE) | 2020-05-26 | — | — | US | disclosed |
| EP-3626472-A1 | LASER MARKABLE COMPOSITIONS | AGFA NV (BE) | 2020-03-25 | — | — | EP | disclosed |
| EP-3626471-A1 | LASER MARKABLE COMPOSITIONS | AGFA NV (BE) | 2020-03-25 | — | — | EP | disclosed |
| EP-2915856-B1 | Etch-resistant inkjet inks for manufacturing conductive patterns | AGFA GEVAERT (BE) | 2019-10-16 | — | — | EP | disclosed |
| EP-3201278-B1 | METHODS OF MANUFACTURING EMBOSSING ELEMENTS | AGFA NV (BE) | 2019-10-09 | — | — | EP | disclosed |
| EP-3201277-B1 | DIGITAL FABRICATION OF METALLIC ARTICLES | AGFA GEVAERT (BE) | 2019-02-20 | — | — | EP | disclosed |
| US-10039193-B2 | Etch-resistant inkjet inks for manufacturing conductive patterns | AGFA-GEVAERT (BE) | 2018-07-31 | — | — | US | disclosed |
| US-9938420-B2 | Digital fabrication of metallic articles | AGFA-GEVAERT (BE) | 2018-04-10 | — | — | US | disclosed |
| EP-3210946-A1 | METHOD OF MANUFACTURING AN ETCHED GLASS ARTICLE | AGFA-GEVAERT (BE) | 2017-08-30 | — | — | EP | disclosed |
| EP-3210947-A1 | METHOD OF MANUFACTURING AN ETCHED GLASS ARTICLE | AGFA-GEVAERT (BE) | 2017-08-30 | — | — | EP | disclosed |
| US-20170226355-A1 | DIGITAL FABRICATION OF METALLIC ARTICLES | AGFA-GEVAERT (BE) | 2017-08-10 | — | — | US | disclosed |
| US-20170218520-A1 | METHODS OF MANUFACTURING EMBOSSING ELEMENTS | AGFA GRAPHICS NV (BE) | 2017-08-03 | — | — | US | disclosed |
| WO-2016050372-A1 | METHODS OF MANUFACTURING EMBOSSING ELEMENTS | AGFA GRAPHICS NV (BE) | 2016-04-07 | — | — | WO | disclosed |
| EP-2915856-A1 | Etch-resistant inkjet inks for manufacturing conductive patterns | AGFA-GEVAERT (BE) | 2015-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069375-A1 | Extracellular Matrices, Uses thereof, and Method for Making Extracellular Matrices | MMP1, MATR3, COL1A1 | TSHR 4786/4885HPGD 842/4885ALDH1A1 676/4885 |
| US-20220175667-A1 | Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices | EPCAM, CD44, MATR3 | TSHR 4799/4885HPGD 1062/4885ALDH1A1 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.