Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934092 | 0.78 | CYP11B2 (0.55) | PIK3CDPDE10A | |
| SCHEMBL14934100 | 0.78 | PIK3CD (0.50) | PIK3CDPDE10A | |
| SCHEMBL19998622 | 0.76 | PDGFRB (0.44) | MAP4K4PTGS2 | |
| SCHEMBL16635368 | 0.75 | PIK3CA (0.49) | PIK3CAKCNH2PI4KBMAP4K4MINK1 | |
| SCHEMBL16068089 | 0.72 | PIK3CD (0.47) | PIK3CAPI4KBPIK3CDPIK3CBPI4KA | |
| SCHEMBL13036072 | 0.72 | AR (0.48) | PIK3CAPI4KBPIK3CDPIK3CBPI4KA | |
| SCHEMBL28242154 | 0.72 | PIK3CA (0.47) | PIK3CAKCNH2PI4KBMAP4K4MINK1 | |
| SCHEMBL16906525 | 0.72 | PIK3CB (0.50) | PIK3CAKCNH2PI4KBMAP4K4MINK1 | |
| SCHEMBL14934093 | 0.72 | PIK3CA (0.52) | PIK3CAPI4KBPIK3CDPIK3CBPI4KA | |
| SCHEMBL17067718 | 0.72 | TRPM8 (0.36) | PIK3CAKCNH2PI4KBMAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |