Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712276 | 0.82 | TSHR (0.46) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL15712189 | 0.81 | ALDH1A1 (0.41) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL17067764 | 0.80 | CYP1A2 (0.36) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL18746328 | 0.78 | SMN1; SMN2 (0.50) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL17067772 | 0.78 | TSHR (0.34) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL21618390 | 0.77 | ALDH1A1 (0.40) | TSHRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL15712209 | 0.77 | FTO (0.34) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL15712662 | 0.76 | CYP19A1 (0.47) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL20850837 | 0.76 | CYP19A1 (0.34) | TSHRTDP1MAPTCYP19A1FTO | |
| SCHEMBL15712760 | 0.76 | MEN1 (0.37) | TSHRTDP1MAPTCYP19A1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915804-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2015-09-09 | — | — | EP | disclosed |