Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027779 | 0.79 | PDGFRB (0.58) | PDGFRBPDGFRACHEK2CHEK1CYP2A6 | |
| SCHEMBL11338752 | 0.77 | CHEK2 (0.49) | PDGFRBPDGFRACHEK2 | |
| SCHEMBL4621645 | 0.76 | CHEK2 (0.67) | PDGFRBPDGFRACHEK2CHEK1CYP2A6 | |
| SCHEMBL992459 | 0.76 | ERN1 (0.53) | PDGFRBPDGFRACHEK2CHEK1CYP2A6 | |
| SCHEMBL3647945 | 0.74 | MAP4K4 (0.62) | CHEK2 | |
| Hydrochloric Acid SCHEMBL11244234 | 0.74 | CHEK2 (0.47) | PDGFRBPDGFRACHEK2 | |
| SCHEMBL17067696 | 0.74 | IDO1 (0.44) | — | |
| SCHEMBL5322817 | 0.74 | CYP2A6 (0.55) | PDGFRBPDGFRACHEK2CHEK1CYP2A6 | |
| SCHEMBL8658633 | 0.74 | CYP2A6 (0.55) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 | |
| SCHEMBL8503219 | 0.73 | PDGFRB (1.00) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |