Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934035 | 0.83 | ALK (0.46) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22183384 | 0.78 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL14648843 | 0.76 | KCNH2 (0.55) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15047763 | 0.75 | CYP1A2 (0.47) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17654918 | 0.75 | CYP1A2 (0.47) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15885599 | 0.73 | PIK3CD (0.43) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12269968 | 0.73 | CYP1A2 (0.49) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12492615 | 0.72 | PIK3CD (0.51) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17067775 | 0.72 | IDO1 (0.51) | KCNH2S1PR1BDKRB2CHRNB2CHRNA4 | |
| SCHEMBL18422297 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |