Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | LDLR | P01130 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 6/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408857 | 0.72 | IDO1 (0.54) | IDO1HPGDSLDLRPCSK9S1PR1 | |
| SCHEMBL17067728 | 0.72 | ALDH1A1 (0.44) | S1PR1CHRNB2CHRNA4BDKRB2KCNH2 | |
| SCHEMBL12492587 | 0.72 | IDO1 (0.58) | IDO1HPGDSS1PR1GSK3BDYRK1A | |
| SCHEMBL13354411 | 0.72 | IDO1 (0.49) | IDO1HPGDSLDLRPCSK9GSK3B | |
| SCHEMBL15875301 | 0.69 | IDO1 (0.64) | IDO1HPGDSLDLRPCSK9S1PR1 | |
| SCHEMBL26953515 | 0.69 | HPGDS (0.59) | IDO1HPGDSLDLRPCSK9GSK3B | |
| SCHEMBL17067678 | 0.69 | JAK2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL14934094 | 0.68 | PDGFRB (0.49) | TTK | |
| SCHEMBL14934167 | 0.68 | MKNK1 (0.41) | CHRNB2CHRNA4KCNH2 | |
| SCHEMBL30039821 | 0.68 | LRRK2 (0.47) | IDO1HPGDSS1PR1LRRK2TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |