Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067680 | 0.78 | CYP11B2 (0.54) | CYP11B2GRM5VRK1CYP11B1CYP2C19 | |
| SCHEMBL14934092 | 0.77 | CYP11B2 (0.55) | CYP11B2VRK1CYP11B1CYP3A4CYP2A6 | |
| SCHEMBL26951603 | 0.76 | GRM5 (0.40) | GRM5CYP3A4CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL14934106 | 0.72 | RPS6KA3 (0.41) | VRK1 | |
| SCHEMBL19998622 | 0.71 | PDGFRB (0.44) | CYP11B2VRK1CYP3A4CYP2C19ABL1 | |
| SCHEMBL13713429 | 0.71 | GRM5 (0.37) | GRM5CNR1 | |
| SCHEMBL14934103 | 0.71 | MAPT (0.43) | CYP11B2CYP11B1PDE2APDE10A | |
| SCHEMBL25699202 | 0.70 | RAF1 (0.39) | GRM5VRK1HDAC4ABL1CHRNB2 | |
| SCHEMBL13713428 | 0.69 | CNR1 (0.33) | GRM5CNR1 | |
| SCHEMBL17946108 | 0.69 | PDGFRB (0.47) | CYP11B2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |