Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067677 | 0.84 | KDM4E (0.42) | CYP11B2CYP11B1MAPTPTGS1PTGS2 | |
| SCHEMBL14934135 | 0.81 | CYP11B2 (0.57) | CYP11B2CYP11B1MAPTMAOAMAOB | |
| SCHEMBL17067745 | 0.78 | CYP11B2 (0.37) | CYP11B2CYP11B1PTGS2PDE2APDE10A | |
| SCHEMBL11245926 | 0.78 | PTGS1 (0.46) | CYP11B2CYP11B1PTGS1PTGS2DHODH | |
| SCHEMBL26951542 | 0.76 | MAOA (0.46) | CYP11B2CYP11B1MAPTDHODHMAOA | |
| SCHEMBL14934106 | 0.75 | RPS6KA3 (0.41) | DHODHVRK1KCNH2 | |
| SCHEMBL13750510 | 0.75 | DHODH (0.46) | CYP11B2CYP11B1MAPTPTGS2DHODH | |
| SCHEMBL17946108 | 0.72 | PDGFRB (0.47) | CYP11B2GRM5 | |
| SCHEMBL15730119 | 0.72 | MKNK1 (0.44) | MAPTPTGS1PTGS2DHODHPDE2A | |
| SCHEMBL14934101 | 0.72 | CYP2A6 (0.56) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |