Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.60 |
| ▸ | CA1 | P00915 | 14/20 | 0.59 |
| ▸ | CA2 | P00918 | 14/20 | 0.59 |
| ▸ | CA12 | O43570 | 6/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598774 | 0.89 | CA9 (0.55) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17067944 | 0.88 | CA9 (0.61) | CA9CA1CA2CA12CA14 | |
| SCHEMBL18517643 | 0.87 | CA9 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14426895 | 0.86 | USP2 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13915130 | 0.85 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12793932 | 0.84 | CA9 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20115479 | 0.84 | CA9 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20622624 | 0.83 | CA9 (0.75) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20059101 | 0.83 | CA9 (0.64) | CA9CA1CA2CA12CA14 | |
| SCHEMBL2742845 | 0.83 | CA9 (0.58) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793027-B1 | Unnatural reactive amino acid genetic code additions | SCRIPPS RESEARCH INST (US) | 2019-11-13 | — | — | EP | disclosed |
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |
| US-9580721-B2 | Expanding the eukaryotic genetic code | The Scripps Reserach Institute (US) | 2017-02-28 | — | — | US | disclosed |