SCHEMBL17068345

SCHEMBL17068345

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nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NFE2L2 Q16236 5/20 0.38
MANBA O00462 1/20 0.37
THRB P10828 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10090616 0.79 LMNA (0.46) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL28150540 0.79 LMNA (0.46) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL16939104 0.79 LMNA (0.46) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL28150541 0.79 LMNA (0.46) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL5903162 0.79 LMNA (0.46) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL31387228 0.78 LMNA (0.44) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL31075347 0.78 LMNA (0.44) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL14097713 0.77 LMNA (0.38) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL28436648 0.75 LMNA (0.36) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL20101941 0.74 NFE2L2 (0.40) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150250169-A1 ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT NIPPON SODA CO., LTD. (JP) 2015-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250169-A1 ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT CBR3, OSR1, OXSR1 LMNA 4569/4885MAPT 4717/4885L3MBTL1 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.