Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17068441 | 0.89 | CYP1A2 (0.37) | CYP1A2GRM2EPHX1ALDH1A1 | |
| SCHEMBL17068454 | 0.87 | CYP1A2 (0.34) | CYP1A2GRM2EPHX1 | |
| SCHEMBL17068525 | 0.86 | KDM1A (0.38) | CYP1A2GRM2 | |
| SCHEMBL17068440 | 0.82 | CYP1A2 (0.36) | CYP1A2GRM2EPHX1ALDH1A1 | |
| SCHEMBL17068749 | 0.82 | RARB (0.37) | CYP1A2GRM2 | |
| SCHEMBL17068746 | 0.80 | OPRL1 (0.33) | CYP1A2GRM2ALDH1A1 | |
| SCHEMBL17068449 | 0.79 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL17068617 | 0.76 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL10600526 | 0.75 | ESR2 (0.40) | CYP1A2GCGRPDE5A | |
| SCHEMBL17070622 | 0.75 | PTGS2 (0.34) | GRM2CYP11B2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523038-B2 | Dihydropyran compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-12-20 | — | — | US | disclosed |
| US-20150252264-A1 | DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252264-A1 | DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | DRD1, CNKSR1, DRG1 | CYP1A2 687/4885GRM2 1891/4885EPHX1 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.