SCHEMBL1706852

SCHEMBL1706852

O=C(c1ccccc1)c1ccc(O)c(O)c1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 2/20 0.50
TDP1 Q9NUW8 2/20 0.48
GAA P10253 1/20 0.48
SLC5A1 P13866 1/20 0.47
SLC5A2 P31639 1/20 0.47
EPHX2 P34913 2/20 0.47
TYR P14679 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA13 Q8N1Q1 1/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PTPN1 P18031 1/20 0.44
MAOB P27338 1/20 0.44
HIF1A Q16665 1/20 0.44
USP2 O75604 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29191289 0.78 SLC28A3 (0.48) SLC28A3TDP1GAASLC5A1SLC5A2
SCHEMBL31345861 0.76 SLC28A3 (0.71) SLC28A3SLC5A1SLC5A2EPHX2KDM4E
SCHEMBL4933738 0.75 KDM4E (0.54) SLC28A3TDP1GAAEPHX2TYR
SCHEMBL1707950 0.75 TYR (0.51) SLC28A3TDP1GAAEPHX2TYR
SCHEMBL4635305 0.75 SLC28A3 (0.61) SLC28A3TDP1SLC5A1SLC5A2EPHX2
SCHEMBL18322971 0.75 SLC28A3 (0.52) SLC28A3TDP1SLC5A1SLC5A2EPHX2
SCHEMBL14120249 0.74 TYR (0.53) SLC28A3TYRMAOB
SCHEMBL28502626 0.74 TYR (0.55) SLC28A3EPHX2TYRCA12CA1
SCHEMBL5181431 0.73 USP2 (0.58) SLC28A3TDP1TYRNPC1RAB9A
SCHEMBL3140292 0.73 USP2 (0.58) SLC28A3TDP1TYRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027279-B1 Phenolic compounds with cosmetic and therapeutic applications LIBRAGEN (FR) 2012-04-18 EP claimed