SCHEMBL1707950

SCHEMBL1707950

O=Cc1ccc(O)c(O)c1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.51
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA13 Q8N1Q1 1/20 0.49
SLC28A3 Q9HAS3 2/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 5/20 0.48
HPGD P15428 4/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
SOST Q9BQB4 1/20 0.47
GAA P10253 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 3/20 0.46
CASP1 P29466 3/20 0.46
CASP7 P55210 3/20 0.46
HSD17B10 Q99714 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989956 0.85 SLC28A3 (0.58) TYRCA12CA1CA7CA9
SCHEMBL988823 0.79 TYR (0.59) TYRSLC28A3HPGDCYP3A4MAPT
SCHEMBL28502626 0.79 TYR (0.55) TYRCA12CA1CA7CA9
Helicin SCHEMBL9844555 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2
Helicin SCHEMBL20723406 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2
Helicin SCHEMBL9888348 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2
Helicin SCHEMBL988045 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2
Helicin SCHEMBL987304 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2
Helicin SCHEMBL1006709 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2
Helicin SCHEMBL9844557 0.76 SLC5A2 (0.57) TYRSLC28A3HIF1AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027279-B1 Phenolic compounds with cosmetic and therapeutic applications LIBRAGEN (FR) 2012-04-18 EP claimed