SCHEMBL17068607

SCHEMBL17068607

CCCC1=COC(C(=O)Oc2ccc(OCC)c(F)c2F)CC1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 11/20 0.36
LTB4R2 Q9NPC1 7/20 0.36
CYSLTR1 Q9Y271 3/20 0.33
CYSLTR2 Q9NS75 2/20 0.33
HPGD P15428 3/20 0.32
TBXAS1 P24557 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17068671 0.83 HPGD (0.37) LTB4RLTB4R2HPGDGLA
SCHEMBL17068618 0.81 HPGD (0.35) LTB4RLTB4R2CYSLTR1CYSLTR2HPGD
SCHEMBL17068461 0.79
SCHEMBL17068677 0.79 CYP2C9 (0.34)
SCHEMBL18006758 0.78 KCNQ3 (0.32) LTB4RLTB4R2HPGD
SCHEMBL17068611 0.77 HTR2A (0.34) GLA
SCHEMBL17068608 0.77 LTB4R (0.34) LTB4RLTB4R2
SCHEMBL17068592 0.76 KDM1A (0.31)
SCHEMBL17068561 0.76 TOP2A (0.35) HPGD
SCHEMBL17068598 0.74 LTB4R (0.34) LTB4RLTB4R2CYSLTR1CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523038-B2 Dihydropyran compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-12-20 US disclosed
US-9523038-B2 Dihydropyran compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-12-20 US disclosed
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-09-10 US disclosed
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252264-A1 DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DRD1, CNKSR1, DRG1 LTB4R 827/4885LTB4R2 610/4885CYSLTR1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.