SCHEMBL1706875

SCHEMBL1706875

NNC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.67
RAB9A P51151 2/20 0.67
CTDSP1 Q9GZU7 1/20 0.67
ALDH1A1 P00352 4/20 0.62
MAPT P10636 4/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
MPO P05164 1/20 0.59
CYP3A4 P08684 1/20 0.59
KDM5A P29375 1/20 0.59
BLM P54132 1/20 0.59
GFER P55789 1/20 0.59
PMP22 Q01453 1/20 0.59
HIF1A Q16665 1/20 0.59
PTPN1 P18031 2/20 0.59
OGG1 O15527 1/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
HPGDS O60760 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5804936 0.98 NPC1 (0.64) NPC1RAB9ACTDSP1ALDH1A1MAPT
SCHEMBL15562870 0.92 MAPT (0.59) NPC1RAB9ACTDSP1ALDH1A1MAPT
SCHEMBL752600 0.91 MPO (0.70) NPC1RAB9ACTDSP1ALDH1A1MAPT
SCHEMBL27661901 0.90 MAPT (0.72) NPC1RAB9ACTDSP1ALDH1A1MAPT
SCHEMBL2834990 0.89 PTPN1 (0.74) NPC1RAB9ACTDSP1MAPTPTPN1
SCHEMBL9386909 0.87 MPO (0.59) NPC1RAB9ACTDSP1ALDH1A1MAPT
SCHEMBL12988648 0.87 ALDH1A1 (0.54) NPC1RAB9ACTDSP1ALDH1A1MAPT
SCHEMBL29290203 0.86 NPC1 (0.51) NPC1RAB9ACTDSP1ALDH1A1MAPT
Benzoic Acid Hydrazide SCHEMBL4515671 0.86 CYP3A4 (0.62) NPC1RAB9AALDH1A1MAPTL3MBTL1
Benzoic Acid Hydrazide SCHEMBL83514 0.86 CYP3A4 (0.62) NPC1RAB9AALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861148-A Quenching type fluorescent probe based on coumarin and preparation method thereof 齐鲁工业大学 2021-12-31 CN claimed
CN-103333674-A Diarylethene photochromic compound with electric field modulation function and synthesis method UNIV TIANJIN CHENGJIAN 2013-10-02 CN claimed
CN-102654696-A Display device and electronic device SEMICONDUCTOR ENERGY LAB 2012-09-05 CN claimed
CN-101101391-B Display device and electronic apparatus SEMINCONDUCTOR ENERGY LAB CO 2012-07-04 CN claimed
CN-101101391-A Display device and electronic apparatus SEMICONDUCTOR ENERGY LAB (JP) 2008-01-09 CN claimed
JP-6184125-A None JP disclosed
US-12559455-B2 Compound as a UBR box domain ligand AUTOTAC INC. (KR) 2026-02-24 US disclosed
EP-4144792-B1 PARTICULATE WATER-ABSORBENT RESIN COMPOSITION, ABSORBENT BODY AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS (JP) 2025-01-08 EP disclosed
EP-4144803-B1 WATER ABSORBENT RESIN COMPOSITION, ABSORBENT, AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS (JP) 2024-12-25 EP disclosed
CN-116730941-B 5-Phenyl-1, 3, 4-oxadiazole compound and preparation method and application thereof 广东省科学院微生物研究所(广东省微生物分析检测中心) 2024-07-02 CN disclosed
CN-115516043-B Particulate water-absorbent resin composition, absorber, and absorbent article 住友精化株式会社 2024-06-28 CN disclosed
CN-115443312-B Water-absorbent resin composition, absorber, and absorbent article 住友精化株式会社 2024-05-14 CN disclosed
WO-1996000148-A1 METHODS FOR THE SOLID PHASE SYNTHESIS OF THIAZOLIDINONES, METATHIAZANONES, AND DERIVATIVES THEREOF AFFYMAX TECHNOLOGIES N.V. (AN) 1996-01-04 WO disclosed
US-5336546-A Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 1994-08-09 US disclosed
JP-H06184125-A 1,3,4-DIAZOLE DERIVATIVE IDEMITSU KOSAN CO LTD 1994-07-05 JP disclosed
WO-1994009773-A1 NEW ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-05-11 WO disclosed
EP-0548366-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-06-30 EP disclosed
US-4125704-A Phenyl-substituted rubidazone analogs SRI INTERNATIONAL (US) 1978-11-14 US disclosed
US-3947410-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1976-03-30 US disclosed
US-3944556-A PHOTOCONDUCTOR, FLUORESCENT, PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559455-B2 Compound as a UBR box domain ligand UBR4, UBTF, UBQLN1 NPC1 2697/4885RAB9A 2068/4885CTDSP1 994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.