Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139433 | 1.00 | CTSS (0.44) | CTSSCTSLCTSBELOVL6FFAR4 | |
| SCHEMBL3799423 | 1.00 | CTSS (0.44) | CTSSCTSLCTSBELOVL6FFAR4 | |
| SCHEMBL3803577 | 1.00 | CTSS (0.44) | CTSSCTSLCTSBELOVL6FFAR4 | |
| SCHEMBL1705616 | 0.86 | CTSS (0.49) | CTSSCTSLCTSBELOVL6CTSK | |
| SCHEMBL1139826 | 0.86 | CTSS (0.49) | CTSSCTSLCTSBELOVL6CTSK | |
| SCHEMBL1140490 | 0.84 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL1705632 | 0.84 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL3801237 | 0.84 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL3796231 | 0.84 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL1139145 | 0.82 | CTSS (0.64) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459162-A | Novel cyclopentane derivatives | HOFFMANN LA ROCHE | 2012-05-16 | — | — | CN | disclosed |
| EP-2440521-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010142650-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |