Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563667 | 0.98 | TAAR1 (0.52) | TAAR1ESR2PAX8HSP90AA1GAA | |
| SCHEMBL28548683 | 0.95 | TAAR1 (0.52) | TAAR1ESR2PAX8CYP3A4CYP17A1 | |
| SCHEMBL28560659 | 0.91 | TAAR1 (0.55) | TAAR1ESR2PAX8CYP3A4CYP17A1 | |
| SCHEMBL16887403 | 0.84 | HSP90AA1 (0.47) | HSP90AA1GAAMAPTKMT2ATDP1 | |
| SCHEMBL11764880 | 0.84 | NPC1 (0.51) | HSP90AA1GAAMAPTKMT2ATDP1 | |
| SCHEMBL10091176 | 0.83 | TAAR1 (0.47) | TAAR1ESR2PAX8CYP3A4CYP17A1 | |
| SCHEMBL16978438 | 0.82 | HSP90AA1 (0.45) | HSP90AA1GAAMAPTKMT2ATDP1 | |
| SCHEMBL15906653 | 0.81 | NOTUM (0.47) | PAX8HSP90AA1GAAMAPTKMT2A | |
| SCHEMBL27830967 | 0.80 | KMO (0.53) | TAAR1GAAKMT2ACYP11B2 | |
| SCHEMBL130265 | 0.80 | KMO (0.53) | TAAR1GAAKMT2ACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493704-B2 | Cycloheptane derivative and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-11-15 | — | — | US | disclosed |
| US-9493704-B2 | Cycloheptane derivative and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-11-15 | — | — | US | disclosed |
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2015-09-10 | — | — | US | disclosed |
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | DHPS, DHCR24, CCNT1 | TAAR1 3786/4885ESR2 3520/4885PAX8 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.