Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070256 | 0.91 | CYP3A4 (0.38) | CYP3A4CYP2C9APPS1PR1FPR2 | |
| SCHEMBL17070266 | 0.89 | ESR2 (0.34) | CYP3A4CYP2C9APPESR2 | |
| SCHEMBL17070253 | 0.89 | ESR2 (0.36) | CYP3A4CYP2C9APPESR2S1PR1 | |
| SCHEMBL17070254 | 0.87 | ESR2 (0.35) | CYP3A4CYP2C9ESR2 | |
| SCHEMBL17070268 | 0.86 | ESR2 (0.34) | CYP3A4CYP2C9ESR2 | |
| SCHEMBL28559153 | 0.85 | ESR2 (0.41) | CYP3A4CYP2C9APPFASNESR2 | |
| SCHEMBL10052063 | 0.85 | ESR2 (0.41) | CYP3A4CYP2C9APPFASNESR2 | |
| SCHEMBL15256178 | 0.84 | ESR2 (0.40) | CYP3A4CYP2C9APPFASNESR2 | |
| SCHEMBL16769036 | 0.83 | KDM1A (0.40) | CYP3A4CYP2C9APPESR2S1PR1 | |
| SCHEMBL21000809 | 0.81 | ESR2 (0.33) | CYP3A4CYP2C9FASNESR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493704-B2 | Cycloheptane derivative and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-11-15 | — | — | US | disclosed |
| US-9493704-B2 | Cycloheptane derivative and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-11-15 | — | — | US | disclosed |
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2015-09-10 | — | — | US | disclosed |
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | DHPS, DHCR24, CCNT1 | CYP3A4 1216/4885CYP2C9 1304/4885APP 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.