Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056526 | 1.00 | KMT2A (0.69) | KMT2AMEN1LMNAMRGPRX4CES2 | |
| SCHEMBL29570653 | 1.00 | KMT2A (0.69) | KMT2AMEN1LMNAMRGPRX4CES2 | |
| Hydrochloric Acid SCHEMBL30779154 | 0.98 | KMT2A (0.67) | KMT2AMEN1LMNAMRGPRX4CES2 | |
| SCHEMBL27403802 | 0.91 | KMT2A (0.60) | KMT2AMEN1LMNAMRGPRX4CES2 | |
| SCHEMBL7470029 | 0.90 | KMT2A (0.58) | KMT2AMEN1LMNAMRGPRX4CES2 | |
| SCHEMBL7829981 | 0.89 | ERN1 (0.58) | KMT2AMEN1LMNAMRGPRX4RAB9A | |
| SCHEMBL30790370 | 0.89 | ERN1 (0.58) | KMT2AMEN1LMNAMRGPRX4RAB9A | |
| Methyl Benzoate SCHEMBL27635675 | 0.88 | TSHR (0.63) | KMT2AMEN1LMNAMRGPRX4CES2 | |
| SCHEMBL4939679 | 0.86 | MRGPRX4 (0.66) | KMT2AMEN1LMNAMRGPRX4RAB9A | |
| SCHEMBL16955045 | 0.86 | NPC1 (0.58) | KMT2AMEN1LMNAMRGPRX4CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957231-B2 | Iodine(II)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170036980-A1 | COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-02-09 | — | — | US | disclosed |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2016-12-15 | — | — | US | disclosed |
| US-9434699-B2 | Iodine(III)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | TPO, FLI1, SSTR3 | KMT2A 1626/4885MEN1 183/4885LMNA 2586/4885 |
| US-20170036980-A1 | COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS | SOD1, TPO, FLI1 | KMT2A 3062/4885MEN1 141/4885LMNA 4678/4885 |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | TPO, FLI1, SSTR3 | KMT2A 1626/4885MEN1 183/4885LMNA 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.