SCHEMBL17070786

SCHEMBL17070786

ONc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.63
MAPT P10636 2/20 0.63
KMT2A Q03164 2/20 0.63
GAA P10253 2/20 0.63
MAPK1 P28482 1/20 0.63
KDM4E B2RXH2 1/20 0.63
RECQL P46063 1/20 0.58
MCL1 Q07820 1/20 0.58
NFKB1 P19838 1/20 0.57
KCNH3 Q9ULD8 6/20 0.57
RHOA P61586 1/20 0.55
LMNA P02545 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
ALDH1A1 P00352 1/20 0.52
IDO1 P14902 1/20 0.50
NPY5R Q15761 1/20 0.50
IDH2 P48735 1/20 0.50
DDX3X O00571 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633400 0.88 MEN1 (0.77) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL18123046 0.83 MEN1 (0.71) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL14921484 0.82 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL12671437 0.80 MAPT (0.61) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL28412986 0.78 MAPT (0.59) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL11797295 0.77 GAA (1.00) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL11936604 0.77 MAPT (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL21914613 0.77 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL1151708 0.77 MEN1 (0.57) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL2253957 0.77 GAA (0.69) MEN1MAPTKMT2AGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9618788-B2 Optical film, polarizing plate and liquid crystal display using the same FUJIFILM CORPORATION (JP) 2017-04-11 US disclosed
US-9618788-B2 Optical film, polarizing plate and liquid crystal display using the same FUJIFILM CORPORATION (JP) 2017-04-11 US disclosed
US-20150253621-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed
US-20150253621-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150253621-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME SSTR3, FFAR3, CNPY3 MEN1 3598/4885MAPT 2510/4885KMT2A 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.