SCHEMBL1151708

SCHEMBL1151708

Oc1nc(O)nc(Nc2ccccc2)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 2/20 0.57
GAA P10253 2/20 0.57
NFKB1 P19838 2/20 0.57
MAPK1 P28482 2/20 0.57
KDM4E B2RXH2 1/20 0.57
RECQL P46063 1/20 0.53
MCL1 Q07820 1/20 0.53
KCNH3 Q9ULD8 4/20 0.52
ALDH1A1 P00352 1/20 0.52
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
NPY5R Q15761 1/20 0.50
RHOA P61586 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
LMNA P02545 2/20 0.48
HSD17B10 Q99714 1/20 0.48
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14921484 0.95 MEN1 (0.63) MEN1MAPTKMT2AGAANFKB1
SCHEMBL14445556 0.86 LMNA (0.69) MEN1MAPTKMT2AGAANFKB1
SCHEMBL11225942 0.86 MEN1 (0.48) MEN1MAPTKMT2AGAANFKB1
SCHEMBL26418166 0.86 NPC1 (0.58) MEN1MAPTKMT2AGAANFKB1
SCHEMBL633400 0.83 MEN1 (0.77) MEN1MAPTKMT2AGAANFKB1
SCHEMBL795053 0.80 GAA (0.47) MEN1MAPTKMT2AGAANFKB1
SCHEMBL12671437 0.80 MAPT (0.61) MEN1MAPTKMT2AGAANFKB1
SCHEMBL9505971 0.80 MEN1 (0.55) MEN1MAPTKMT2AGAANFKB1
SCHEMBL28888084 0.79 SYK (0.58) MEN1KMT2AADORA2AADORA1TSHR
SCHEMBL5137042 0.79 BCL6 (0.62) MEN1MAPTKMT2AGAANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8864851-B2 Compositions of fluorescent whitening agents 3V SIGMA S.P.A. (IT) 2014-10-21 US claimed
US-20140252262-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS 3V SIGMA S.P.A. (IT) 2014-09-11 US claimed
EP-2773627-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS 3V SIGMA S.p.A (IT) 2014-09-10 EP claimed
WO-2013064946-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS 3V SIGMA S.P.A. (IT) 2013-05-10 WO claimed
CN-117363124-A Coating liquid composition for display and organic coating film using the same 株式会社特雷尔 2024-01-09 CN disclosed
US-11352511-B2 Dispersant, dispersant composition, dispersion composition for batteries, electrode and battery TOYO INK SC HOLDINGS CO., LTD. (JP) 2022-06-07 US disclosed
US-20200131379-A1 DISPERSANT, DISPERSANT COMPOSITION, DISPERSION COMPOSITION FOR BATTERIES, ELECTRODE AND BATTERY TOYO INK SC HOLDINGS CO., LTD. (JP) 2020-04-30 US disclosed
EP-2224036-B1 RESIN-METAL BONDED ARTICLE AND METHOD FOR PRODUCING THE SAME TOADENKA CORP (JP) 2016-03-16 EP disclosed
US-8864851-B2 Compositions of fluorescent whitening agents 3V SIGMA S.P.A. (IT) 2014-10-21 US disclosed
US-20140252262-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS 3V SIGMA S.P.A. (IT) 2014-09-11 US disclosed
EP-2773627-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS 3V SIGMA S.p.A (IT) 2014-09-10 EP disclosed
WO-2013064946-A1 COMPOSITIONS OF FLUORESCENT WHITENING AGENTS 3V SIGMA S.P.A. (IT) 2013-05-10 WO disclosed
US-8394503-B2 Resin-metal bonded article and method for producing the same TOADENKA CORPORATION (JP) 2013-03-12 US disclosed
US-20110033711-A1 RESIN-METAL BONDED ARTICLE AND METHOD FOR PRODUCING THE SAME DENSO CORPORATION (JP) 2011-02-10 US disclosed