SCHEMBL633400

SCHEMBL633400

c1ccc(Nc2nc(Nc3ccccc3)nc(Nc3ccccc3)n2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.77
MAPT P10636 2/20 0.77
KMT2A Q03164 2/20 0.77
GAA P10253 2/20 0.77
MAPK1 P28482 2/20 0.77
KDM4E B2RXH2 1/20 0.77
NFKB1 P19838 1/20 0.70
KCNH3 Q9ULD8 5/20 0.68
RECQL P46063 1/20 0.63
MCL1 Q07820 1/20 0.63
LMNA P02545 1/20 0.63
ALDH1A1 P00352 2/20 0.61
HSD17B10 Q99714 2/20 0.61
NPY5R Q15761 1/20 0.59
RHOA P61586 1/20 0.59
IDH2 P48735 1/20 0.59
DDX3X O00571 1/20 0.59
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
ALOX12 P18054 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18123046 0.95 MEN1 (0.71) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL8506448 0.88 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL21914613 0.88 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL17070786 0.88 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL11797295 0.88 GAA (1.00) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL1923883 0.88 MAPT (1.00) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL14921484 0.88 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL11936604 0.88 MAPT (0.63) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL2253957 0.88 GAA (0.69) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL11223213 0.88 MEN1 (0.63) MEN1MAPTKMT2AGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569414-B2 Sunscreen compositions containing porous metal oxide spheres BASF SE (DE) 2026-03-10 US claimed
US-20250099345-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2025-03-27 US claimed
US-20250090429-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2025-03-20 US claimed
EP-4465949-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2024-11-27 EP claimed
EP-4465950-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2024-11-27 EP claimed
WO-2023139038-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO claimed
WO-2023139037-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO claimed
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-06-16 US claimed
EP-3937883-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-01-19 EP claimed
EP-3481365-B1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2021-09-08 EP claimed
US-20020028186-A1 Composition containing sapogenin L'OREAL (FR) 2002-03-07 US claimed
US-6294157-B1 AND A SOLUBILIZING SYSTEM COMPRISING: (A) NON-EMULSIFYING ESTER OF A FATTY ACID AND/OR OF A FATTY ALCOHOL, OR A PLANT OIL, AND (B) AT LEAST ONE BRANCHED FATTY ALCOHOL WHOSE HYDROCARBON-BASED CHAIN CONTAINS AT LEAST 8 CARBON ATOMS, L'OREAL (FR) 2001-09-25 US claimed
US-6235271-B1 A SUNSCREEN AGENT COMPRISING A MICRONIZED ORGANIC ULTRAVIOLET ABSORBER, AN OIL SOLUBLE, NON-MICRONIZED ULTRAVIOLET ABSORBER AND/OR INORGANIC MICROPIGMENT AND A COPOLYMER OF ACRYLIC ACID-STYRENE AS HOLLOW SPHERE CIBA SPECIALTY CHEMICALS CORPORATION 2001-05-22 US claimed
US-6221342-B1 PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE DAMAGING EFFECT OF UV RADIATION CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-24 US claimed
EP-1092422-A1 Composition, particularly for cosmetics containing a sapogenin L'OREAL (FR) 2001-04-18 EP claimed
EP-1089706-A1 SUN SCREEN FORMULATIONS Ciba SC Holding AG (CH) 2001-04-11 EP claimed
EP-1050296-A1 Composition containing at least a bicyclic aromatic compound and at least a lipopholic sunscreen, and its uses L'OREAL (FR) 2000-11-08 EP claimed
US-6090370-A TREATING THE HAIR WITH A COSMETIC FORMULATION COMPRISING PROTECTIVE AMONUNT OF A BENZOTRIAZOLE COMPOUND FOR PROTECTING HUMAN HAIR FROM HARMFUL EFFECT OF ULTRAVIOLET RADIATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-07-18 US claimed
WO-1999066896-A1 SUN SCREEN FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-29 WO claimed
EP-0893119-A1 UV-protection formulation Ciba SC Holding AG (CH) 1999-01-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES SDHB, SDHA, MCM5 MEN1 759/4885MAPT 2905/4885KMT2A 2209/4885
US-20020028186-A1 Composition containing sapogenin CYP46A1, FASN, ASAH2 MEN1 4653/4885MAPT 909/4885KMT2A 4055/4885
US-20250099345-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES SUN2, ERCC4, XPA MEN1 1291/4885MAPT 2760/4885KMT2A 3608/4885
US-20250090429-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES ERCC4, SUN2, ERCC5 MEN1 1535/4885MAPT 2571/4885KMT2A 3480/4885
US-12569414-B2 Sunscreen compositions containing porous metal oxide spheres RAD50, CTSA, MCM7 MEN1 1209/4885MAPT 2853/4885KMT2A 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.