Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707095 | 1.00 | SLC6A3 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL1707440 | 0.99 | SLC6A3 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL1706805 | 0.99 | SLC6A3 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL1706803 | 0.99 | SLC6A3 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL1707677 | 0.95 | HDAC1 (0.42) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL1707679 | 0.95 | HDAC1 (0.42) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL1707198 | 0.94 | HDAC1 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL1707202 | 0.94 | HDAC1 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL1707307 | 0.94 | HDAC1 (0.41) | SLC6A3HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL1706819 | 0.92 | SLC6A3 (0.43) | SLC6A3MAPK1CCR3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | claimed |
| EP-1981877-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2008-10-22 | — | — | EP | claimed |
| WO-2007091703-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2007-08-16 | — | — | WO | claimed |
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |