Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707677 | 1.00 | HDAC1 (0.42) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL1707198 | 0.99 | HDAC1 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL1707307 | 0.99 | HDAC1 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL1707202 | 0.99 | HDAC1 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL1707095 | 0.95 | SLC6A3 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL1707102 | 0.95 | SLC6A3 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL1706805 | 0.94 | SLC6A3 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL1706803 | 0.94 | SLC6A3 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL1707440 | 0.94 | SLC6A3 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL4222392 | 0.92 | CCR3 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | claimed |
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |