Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245649 | 0.86 | PIM1 (0.47) | GAAPIM1KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27295009 | 0.85 | PIM1 (0.46) | GAAPIM1KDM4EALDH1A1TSHR | |
| SCHEMBL6247630 | 0.84 | TSHR (0.58) | GAAKDM4EALDH1A1TSHRRAB9A | |
| SCHEMBL29018867 | 0.82 | MAPT (0.52) | GAAKDM4EALDH1A1TSHRMAPT | |
| SCHEMBL987450 | 0.82 | ALDH1A1 (0.47) | GAAPIM1KDM4EALDH1A1TSHR | |
| SCHEMBL13724523 | 0.82 | MAPT (0.47) | GAAKDM4EALDH1A1TSHRMAPT | |
| SCHEMBL4520980 | 0.81 | ACHE (0.46) | GAAKDM4EALDH1A1TSHRRAB9A | |
| SCHEMBL511275 | 0.80 | CYP3A4 (0.50) | GAAPIM1KDM4EALDH1A1TSHR | |
| SCHEMBL5328403 | 0.79 | CYP3A4 (0.48) | GAAKDM4EALDH1A1TSHRRAB9A | |
| SCHEMBL1144609 | 0.79 | TSHR (0.62) | GAAKDM4EALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133099-B2 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | NOGRA PHARMA LIMITED (IE) | 2015-09-15 | — | — | US | disclosed |