⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27885472 | 0.89 | KDM4E (0.36) | — | |
| SCHEMBL11126638 | 0.85 | CA1 (0.30) | — | |
| SCHEMBL16851 | 0.85 | — | — | |
| Fluoride SCHEMBL27474380 | 0.85 | — | — | |
| Water SCHEMBL8763582 | 0.82 | — | — | |
| SCHEMBL29401883 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28169082 | 0.82 | — | — | |
| SCHEMBL28610358 | 0.82 | — | — | |
| SCHEMBL5496029 | 0.82 | — | — | |
| SCHEMBL28146323 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169273-B | Dihydrofuran azetidine derivatives as antiparasitic | 硕腾服务有限责任公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-104169273-B | Dihydrofuran azetidine derivatives as antiparasitic | 硕腾服务有限责任公司 | 2016-11-02 | — | — | CN | disclosed |
| US-9133172-B2 | Dihydrofuran azetidine derivatives as antiparasitic agents | ZOETIS SERVICES LLC (US) | 2015-09-15 | — | — | US | disclosed |
| CN-104169273-A | Dihydrofuran azetidine derivatives as antiparasitic agents | ZOETIS LLC | 2014-11-26 | — | — | CN | disclosed |
| CN-104169273-A | Dihydrofuran azetidine derivatives as antiparasitic agents | ZOETIS LLC | 2014-11-26 | — | — | CN | disclosed |