Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28234853 | 0.83 | — | — | |
| SCHEMBL20584678 | 0.82 | — | — | |
| SCHEMBL31456852 | 0.82 | — | — | |
| SCHEMBL20584679 | 0.82 | — | — | |
| SCHEMBL31067442 | 0.82 | — | — | |
| SCHEMBL17064413 | 0.82 | — | — | |
| SCHEMBL20584680 | 0.82 | — | — | |
| SCHEMBL17064475 | 0.78 | ADRB1 (0.35) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL25805122 | 0.78 | — | — | |
| SCHEMBL17064402 | 0.77 | DUT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015134998-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2015-09-11 | — | — | WO | disclosed |