Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CCKBR | P32239 | 6/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16869921 | 0.97 | CCKBR (0.53) | CTSLCCKBRRENMAPTKLK7 | |
| SCHEMBL17073778 | 0.91 | CTSL (0.64) | CTSLCCKBRRENMAPTKLK7 | |
| SCHEMBL21627146 | 0.91 | CCKBR (0.51) | CCKBRREN | |
| SCHEMBL16862447 | 0.91 | CCKBR (0.51) | CCKBRREN | |
| SCHEMBL18659578 | 0.90 | CCKBR (0.46) | CTSLCCKBRRENKLK7KLK5 | |
| SCHEMBL20794791 | 0.90 | CCKBR (0.55) | CCKBRREN | |
| SCHEMBL18659587 | 0.90 | CTSL (0.47) | CTSLCCKBRRENMAPTKLK7 | |
| SCHEMBL18659589 | 0.89 | KLK7 (0.46) | CTSLCCKBRMAPTKLK7KLK5 | |
| SCHEMBL16869898 | 0.87 | MAPT (0.59) | CTSLCCKBRRENMAPTKLK7 | |
| SCHEMBL20653746 | 0.87 | CTSL (0.67) | CTSLCCKBRRENMAPTKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081363-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | STEALTH BIOTHERAPEUTICS CORP (MC) | 2017-03-23 | — | — | US | disclosed |
| WO-2015134096-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | STEALTH PEPTIDES INTERNATIONAL, INC. (MC) | 2015-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081363-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | ADM2, VIP, ANPEP | CTSL 200/4885CCKBR 135/4885REN 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.