Urea

Urea

SCHEMBL17075255

NC(N)=O.O=CC(O)c1ccco1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
POLB P06746 2/20 0.50
PTPN1 P18031 2/20 0.50
PKM P14618 1/20 0.50
PTPN7 P35236 1/20 0.50
BLM P54132 1/20 0.50
ESR2 Q92731 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALOX5 P09917 3/20 0.46
MEN1 O00255 4/20 0.46
AGTR1 P30556 1/20 0.46
CYP2C19 P33261 2/20 0.45
ALDH1A1 P00352 4/20 0.43
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MIF P14174 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL525254 0.92
SCHEMBL9984097 0.71
SCHEMBL28988497 0.71
SCHEMBL5642277 0.71
SCHEMBL21139852 0.70 KMT2A (0.49) KMT2APOLBPTPN1PKMPTPN7
SCHEMBL8141474 0.70 ALDH1A1 (0.46) KMT2APOLBPTPN1PKMPTPN7
Hydrochloric Acid SCHEMBL15547303 0.69 ALDH1A1 (0.41) KMT2APOLBPTPN1PKMPTPN7
SCHEMBL15942167 0.69 KMT2A (0.45) KMT2APOLBPTPN1PKMPTPN7
Furfural SCHEMBL3040274 0.69 ALDH1A1 (0.78) KMT2APOLBBLML3MBTL1ALOX5
SCHEMBL3972844 0.69 KMT2A (0.50) KMT2APOLBPTPN1PKMPTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150259566-A1 METHODS FOR PROVIDING A LOW GLOSS POLYURETHANE COATING ON A SUBSTRATE BAYER MATERIALSCIENCE LLC (US) 2015-09-17 US disclosed
WO-2015138227-A1 METHODS FOR PROVIDING A LOW GLOSS POLYURETHANE COATING ON A SUBSTRATE BAYER MATERIALSCIENCE LLC (US) 2015-09-17 WO disclosed