Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 17/20 | 0.67 |
| ▸ | FEN1 | P39748 | 17/20 | 0.67 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15916366 | 0.80 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL15915736 | 0.79 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL17075748 | 0.78 | ALOX5AP (0.62) | ALOX5APFEN1SLC6A9SCN9A | |
| SCHEMBL17075746 | 0.75 | ALOX5AP (0.57) | ALOX5APFEN1SLC6A9SCN9A | |
| SCHEMBL15915734 | 0.71 | FEN1 (0.86) | ALOX5APFEN1 | |
| SCHEMBL20627559 | 0.69 | ALOX5AP (0.77) | ALOX5APFEN1 | |
| SCHEMBL15915900 | 0.68 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL14440752 | 0.68 | ALOX5AP (0.55) | ALOX5APFEN1SCN9A | |
| SCHEMBL15918106 | 0.67 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL20627567 | 0.67 | FEN1 (0.77) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884878-B2 | FLAP modulators | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-06 | — | — | US | disclosed |
| US-20150259357-A1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259357-A1 | FLAP MODULATORS | PGF, FEN1, TBXA2R | ALOX5AP 80/4885FEN1 2/4885SLC6A9 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.