Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791951 | 0.85 | MRGPRX4 (0.68) | MRGPRX4MAOBSMN1; SMN2ALDH1A1CCR5 | |
| SCHEMBL30054184 | 0.85 | MRGPRX4 (0.68) | MRGPRX4MAOBSMN1; SMN2ALDH1A1CCR5 | |
| SCHEMBL6827590 | 0.85 | MRGPRX4 (0.64) | MRGPRX4MAOBIDO1AGXTSLC6A4 | |
| SCHEMBL29826082 | 0.84 | MRGPRX4 (0.65) | MRGPRX4MAOBIDO1AGXTSMN1; SMN2 | |
| SCHEMBL14855309 | 0.83 | CCR5 (0.52) | MRGPRX4MAOBIDO1SMN1; SMN2CCR5 | |
| SCHEMBL632895 | 0.83 | MRGPRX4 (0.57) | MRGPRX4MAOBSMN1; SMN2NPC1MAPT | |
| SCHEMBL22180758 | 0.82 | MRGPRX4 (0.58) | MRGPRX4SMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL156718 | 0.82 | MAOB (0.61) | MRGPRX4MAOBIDO1AGXT | |
| SCHEMBL12269218 | 0.82 | MAOB (0.51) | MRGPRX4MAOBIDO1AGXTSMN1; SMN2 | |
| SCHEMBL29388015 | 0.82 | MAOB (0.61) | MRGPRX4MAOBIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259331-A1 | PROTOZOAN PARASITE GROWTH INHIBITORS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259331-A1 | PROTOZOAN PARASITE GROWTH INHIBITORS | TPP1, MKI67, PIGO | MRGPRX4 3036/4885MAOB 1396/4885IDO1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.