Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | ROS1 | P08922 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886091 | 0.94 | EGFR (0.62) | EGFRERBB2CLK4CHEK2ROS1 | |
| SCHEMBL17075865 | 0.88 | EGFR (0.61) | EGFRERBB2 | |
| SCHEMBL17075814 | 0.88 | MAPK1 (0.63) | EGFRCLK4PI4KBMAPK1MAPT | |
| SCHEMBL4891690 | 0.84 | MAPK1 (0.59) | EGFRERBB2CLK4CHEK2ROS1 | |
| SCHEMBL14026142 | 0.84 | MAPK1 (0.72) | CLK4PI4KBMAPK1MAPTAHR | |
| SCHEMBL4008515 | 0.81 | MAPT (0.80) | EGFRCLK4PI4KBMAPK1MAPT | |
| SCHEMBL17075844 | 0.81 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL17083341 | 0.81 | EGFR (0.60) | EGFRERBB2 | |
| SCHEMBL4892996 | 0.81 | PI4KB (0.57) | EGFRERBB2CLK4FLT3AURKB | |
| SCHEMBL4791053 | 0.79 | MAPT (0.61) | EGFRCLK4AURKBPI4KBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259331-A1 | PROTOZOAN PARASITE GROWTH INHIBITORS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259331-A1 | PROTOZOAN PARASITE GROWTH INHIBITORS | TPP1, MKI67, PIGO | EGFR 4389/4885ERBB2 4468/4885CLK4 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.