Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | ILK | Q13418 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759642 | 0.95 | SRC (0.60) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4759186 | 0.88 | MAPT (0.57) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4940130 | 0.87 | KDR (0.62) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4937051 | 0.87 | KDR (0.62) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4007243 | 0.87 | CYP1A2 (0.67) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4008515 | 0.86 | MAPT (0.80) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4886091 | 0.84 | EGFR (0.62) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4010987 | 0.84 | ALDH1A1 (0.64) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL4937677 | 0.83 | SRC (0.57) | MAPTMAPK1AHRHTTPI4KB | |
| SCHEMBL14026142 | 0.83 | MAPK1 (0.72) | MAPTMAPK1AHRHTTPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991533-A1 | CHEMICAL COMPOUNDS | Arrow Therapeutics Limited (GB) | 2008-11-19 | — | — | EP | disclosed |
| US-20080267914-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | US | disclosed |
| WO-2007042782-A1 | CHEMICAL COMPOUNDS | ARROW THERAPEUTICS LIMITED (GB) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267914-A1 | Chemical Compounds | RNASEL, ZC3HAV1L, RNASEH1 | MAPT 4645/4885MAPK1 1706/4885AHR 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.