Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096547 | 0.97 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL5502611 | 0.97 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL75867 | 0.97 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3096537 | 0.97 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL12213295 | 0.97 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL16909341 | 0.94 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL31620295 | 0.94 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8031288 | 0.94 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Ethylene Glycol SCHEMBL28869316 | 0.90 | LMNA (0.56) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Acetic Acid SCHEMBL18759625 | 0.85 | LMNA (0.58) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895517-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | claimed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | claimed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | disclosed |