Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12213295 | 1.00 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL5502611 | 1.00 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL75867 | 1.00 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3096537 | 1.00 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL16909341 | 0.97 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL17075907 | 0.97 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL31620295 | 0.97 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8031288 | 0.97 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Ethylene Glycol SCHEMBL28869316 | 0.92 | LMNA (0.56) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Acetic Acid SCHEMBL18759625 | 0.88 | LMNA (0.58) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629268-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-01-14 | — | — | US | disclosed |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-02-21 | — | — | US | disclosed |
| US-8227645-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-07-24 | — | — | US | disclosed |
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-09-09 | — | — | US | disclosed |
| US-6031127-A | Process for preparing L-p-boronophenylalanine and intermediate for preparing the same | TOHOKU UNIVERSITY (JP) | 2000-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | DHPS, GGPS1, COASY | LMNA 2075/4885KDM4E 2747/4885L3MBTL1 4638/4885 |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | COASY, AKR1C4, AKR1C2 | LMNA 2022/4885KDM4E 3322/4885L3MBTL1 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.