SCHEMBL1707608

SCHEMBL1707608

Nc1nc(N)nc(Cc2nc(N)nc(N)n2)n1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.58
CYP1A2 P05177 1/20 0.48
LMNA P02545 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
HTR6 P50406 7/20 0.32
HRH4 Q9H3N8 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5670278 0.80 CASP1 (0.52) CASP1CYP1A2LMNASMN1; SMN2HTT
SCHEMBL4448651 0.79 CASP1 (0.77) CASP1CYP1A2LMNASMN1; SMN2HTT
SCHEMBL29485005 0.76
SCHEMBL29900242 0.76
SCHEMBL8356506 0.76 CASP1 (0.50) CASP1CYP1A2LMNASMN1; SMN2NPC1
SCHEMBL29876207 0.76
SCHEMBL9579151 0.76 CASP1 (0.50) CASP1CYP1A2LMNASMN1; SMN2NPC1
SCHEMBL8465809 0.76 CASP1 (0.50) CASP1CYP1A2LMNASMN1; SMN2NPC1
SCHEMBL25853 0.76
SCHEMBL3416553 0.74 HTR6 (0.57) CYP1A2LMNASMN1; SMN2HTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089072-A1 POLYACETAL RESIN COMPOSITION ポリプラスチックス株式会社 2025-05-01 WO disclosed
WO-2025089071-A1 POLYACETAL RESIN COMPOSITION ポリプラスチックス株式会社 2025-05-01 WO disclosed
CN-118055976-B Polyacetal resin composition 宝理塑料株式会社 2025-04-11 CN disclosed
CN-118055975-B Polyacetal resin composition 宝理塑料株式会社 2025-03-07 CN disclosed
CN-118055976-A Polyacetal resin composition 宝理塑料株式会社 2024-05-17 CN disclosed
CN-118055975-A Polyacetal resin composition 宝理塑料株式会社 2024-05-17 CN disclosed
CN-113906098-B Polyacetal resin composition and method for producing same 宝理塑料株式会社 2023-11-10 CN disclosed
WO-2023058402-A1 POLYACETAL RESIN COMPOSITION ポリプラスチックス株式会社 2023-04-13 WO disclosed
CN-113906098-A Polyacetal resin composition and method for producing same 宝理塑料株式会社 2022-01-07 CN disclosed
US-11142637-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2021-10-12 US disclosed
EP-2647666-A1 Tribologically modified polyoxymethylene Ticona GmbH (DE) 2013-10-09 EP disclosed
EP-2441786-B1 Glass-fiber reinforced polyoxymethylene TICONA GMBH (DE) 2013-07-31 EP disclosed
US-20130102718-A1 Tribologically Modified Glass-Fiber Reinforced Polyoxymethylene TICONA GMBH (DE) 2013-04-25 US disclosed
WO-2013053914-A1 TRIBOLOGICALLY MODIFIED GLASS-FIBER REINFORCED POLYOXYMETHYLENE TICONA GMBH (DE) 2013-04-18 WO disclosed
EP-2581408-A1 Tribologically modified glass-fiber reinforced polyoxymethylene Ticona GmbH (DE) 2013-04-17 EP disclosed
US-20120157588-A1 Glass Fiber-Reinforced Polyoxymethylene TICONA GMBH (DE) 2012-06-21 US disclosed
EP-2441786-A1 Glass-fiber reinforced polyoxymethylene Ticona GmbH (DE) 2012-04-18 EP disclosed
US-7619020-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-11-17 US disclosed
US-20080039567-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2008-02-14 US disclosed
EP-1887043-A1 Polyacetal resin composition Polyplastics Co., Ltd. (JP) 2008-02-13 EP disclosed