SCHEMBL170764

SCHEMBL170764

C=CCC(C)N1CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.34
ALDH1A1 P00352 4/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
USP2 O75604 1/20 0.30
KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232221 0.81 KMT2A (0.39) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL11729034 0.79 LMNA (0.39) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL27823416 0.79 KMT2A (0.38) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL300143 0.76 KMT2A (0.41) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL1477384 0.76 KMT2A (0.41) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL28486993 0.75 CHRM5 (0.31) KMT2AMEN1
SCHEMBL23108665 0.73 KMT2A (0.42) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL21564194 0.73 KMT2A (0.42) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL643674 0.73 KMT2A (0.42) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL8650528 0.72 KMT2A (0.46) KMT2AMEN1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110300091-A1 TRANSLUCENT DEODORANT STICKS CONTAINING SOLUBILIZED 3,4,4'-TRICHLOROCARBANILIDE THE DIAL CORPORATION (US) 2011-12-08 US claimed
EP-4355433-A1 SUSPENDING POLYMER COMPOSITION AND METHOD OF USE THEREOF ISP Investments LLC (US) 2024-04-24 EP disclosed
US-20230193160-A1 A SUSPENDING POLYMER COMPOSITION, AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2023-06-22 US disclosed
US-20230167060-A1 COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE ATHENEX, INC. 2023-06-01 US disclosed
EP-4157987-A1 A SUSPENDING POLYMER COMPOSITION, AND METHOD OF USE THEREOF ISP Investments LLC (US) 2023-04-05 EP disclosed
WO-2023009315-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2023-02-02 WO disclosed
WO-2022266161-A1 SUSPENDING POLYMER COMPOSITION AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2022-12-22 WO disclosed
WO-2021243198-A1 A SUSPENDING POLYMER COMPOSITION, AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2021-12-02 WO disclosed
US-20190263755-A1 COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE KINEX PHARMACEUTICALS, LLC 2019-08-29 US disclosed
US-9931290-B2 Acrylate copolymer thickeners LUBRIZOL ADVANCED MATERIALS, INC. (US) 2018-04-03 US disclosed
WO-1999038486-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-08-05 WO disclosed
WO-1999038485-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-08-05 WO disclosed
WO-1998055089-A1 COSMETIC COMPOSITIONS COMPRISING A PROTEINACEOUS MATERIAL AND A POLYOLESTER THE PROCTER & GAMBLE COMPANY (US) 1998-12-10 WO disclosed
WO-1998022075-A2 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-05-28 WO disclosed
EP-0706365-A4 COSMETIC MAKE-UP COMPOSITIONS PROCTER & GAMBLE (US) 1998-03-25 EP disclosed
US-5688831-A LIQUID CRYSTALS THE PROCTER & GAMBLE COMPANY (US) 1997-11-18 US disclosed
EP-0778765-A1 COSMETIC MAKE-UP COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-06-18 EP disclosed
WO-1996011665-A1 COSMETIC MAKE-UP COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-04-25 WO disclosed
EP-0706365-A1 COSMETIC MAKE-UP COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-04-17 EP disclosed
WO-1994028860-A1 COSMETIC MAKE-UP COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1994-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167060-A1 COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE MAP3K1, MAP3K6, MAP3K11 KMT2A 1990/4885MEN1 1821/4885LMNA 2550/4885
US-20190263755-A1 COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE MAP3K1, MAP3K11, MAP3K6 KMT2A 1568/4885MEN1 1654/4885LMNA 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.