SCHEMBL17077971

SCHEMBL17077971

O=S(=O)(OF)c1ccc(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
HSD17B10 Q99714 1/20 0.38
PKM P14618 1/20 0.37
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1350979 0.84 LMNA (0.39) LMNAHSD17B10PKMCES2CES1
SCHEMBL15352604 0.81 LMNA (0.37) LMNAHSD17B10PKMCES2CES1
SCHEMBL16467618 0.81 LMNA (0.41) LMNAHSD17B10PKMCES2CES1
SCHEMBL6114511 0.79 LMNA (0.40) LMNAHSD17B10PKMCES2CES1
SCHEMBL217115 0.78 CA12 (0.35)
SCHEMBL29668868 0.77 HSD17B10 (0.40) LMNAHSD17B10PKMCES2CES1
SCHEMBL533092 0.77 HSD17B10 (0.40) LMNAHSD17B10PKMCES2CES1
SCHEMBL29203696 0.77 LMNA (0.42) LMNAHSD17B10PKMCES2CES1
SCHEMBL28771828 0.75 LMNA (0.41) LMNAHSD17B10PKMCES2CES1
SCHEMBL2047328 0.75 LMNA (0.41) LMNAHSD17B10PKMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327239-A Preparation method and application of ether-bond-free poly-aromatic tetrafluorophenyl phosphonated and sulfonated polymer and proton exchange membrane thereof 中国科学院大连化学物理研究所 2024-01-02 CN disclosed
US-10258932-B2 Porous carbon films UTI LIMITED PARTNERSHIP (CA) 2019-04-16 US disclosed
CN-105874550-B Carrying body and photo-electric conversion element 株式会社艾迪科 2018-08-14 CN disclosed
US-20170014780-A1 POROUS CARBON FILMS MOMENTUM MATERIALS CORPORATION (CA) 2017-01-19 US disclosed
WO-2015135069-A1 POROUS CARBON FILMS UTI LIMITED PARTNERSHIP (CA) 2015-09-17 WO disclosed
CN-103801394-A Organic modified hydrophobic nano solid acid material and preparation thereof DALIAN CHEMICAL PHYSICS INST 2014-05-21 CN disclosed