Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078207 | 0.85 | SLC28A3 (0.64) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| SCHEMBL1707950 | 0.85 | TYR (0.51) | SLC28A3HIF1ATYREPHX2ALDH1A1 | |
| SCHEMBL9563927 | 0.82 | ALDH1A1 (0.47) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL987304 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL1006709 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL988045 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL9844557 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL9888348 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL20723406 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 | |
| Helicin SCHEMBL9844555 | 0.82 | SLC5A2 (0.57) | SLC28A3HIF1ATYREPHX2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271350-A1 | COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY | Cognate3, LLC. (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009145841-A1 | COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY | COGNATE 3, LLC (US) | 2009-12-03 | — | — | WO | disclosed |